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【Entocir (budesonide) 布地奈德药品简介】

Entocir（budesonide 布地奈德）是一线抗炎药和局部作用的糖皮质激素，用于诱导和维持轻度至中度回盲肠克罗恩病（胶囊）和溃疡性结肠炎（灌肠）的缓解以及活性物质的缓解。显微镜结肠炎（胶囊）。Entocir有两种配方，胶囊和灌肠剂，可在40多个国家使用。



【Entocir (budesonide) 布地奈德作用机制】

布地奈德是一种抗炎皮质类固醇，具有高糖皮质激素作用和弱的盐皮质激素作用，布地奈德对糖皮质激素受体的亲和力，反映了药物的内在效力，是皮质醇的200倍，是皮质醇的15倍。



【Entocir (budesonide) 布地奈德适应症和用法】

Entocir是一种皮质类固醇，适用于：

治疗8岁及以上患者的轻度至中度活动性克罗恩病，包括回肠和/或升结肠。

在成人中维持轻度至中度克罗恩病的临床缓解，包括回肠和/或升结肠长达3个月。



【Entocir (budesonide) 布地奈德剂量和给药】

管理说明：

每天早上服用一次。吞下整个。不要咀嚼或压碎。对于无法吞咽完整胶囊的患者，打开胶囊，将颗粒倒入一汤匙苹果酱中。在30分钟内混合并消耗全部内容。不要咀嚼或压碎。跟着8盎司的水。在治疗期间避免食用葡萄柚汁。



【Entocir (budesonide) 布地奈德推荐用量】：

1.轻度至中度活动性克罗恩病：

成人：每日9毫克，最长8周;重复8周的治疗过程，反复发作活动性疾病。

体重超过25公斤的儿科8至17岁：每天一次9毫克，最长8周，然后每天早上6毫克，持续2周。

维持轻度至中度克罗恩病的临床缓解

成人：每日6毫克，最长3个月;锥形完成3个月后停止。尚未证实持续治疗超过3个月可提供实质性临床益处。

从口服泼尼松龙转换时，开始逐渐减量泼尼松龙，同时开始使用Entocir。

2.肝功能损害：

考虑将中度肝功能损害的成人患者每日一次减少至3mg（Child-Pugh B级）。





【Entocir (budesonide) 布地奈德禁忌症】

对布地奈德片任何成分过敏者。



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